49ers vs Vikings: AI Prediction - NFL Picks for Todays Game

The San Francisco 49ers and Minnesota Vikings face off Sunday at US Bank Stadium in what promises to be an exciting NFL matchup. This game offers plenty of intrigue, both from a football and betting perspective. As we break down the game, we will analyze the key factors to help make a solid prediction and identify the best pick for this Vikings vs. 49ers contest. Looking at recent form, head-to-head stats, and team dynamics, we’ll consider betting trends, injuries, and any other relevant data to determine the best wagering strategy.

Preview of Vikings vs 49ers AI Predictions

Our AI Picks have you covered for this game + many more

49ers Preview 

San Francisco began their preseason with a 17-13 loss to the Tennessee Titans, but bounced back in game two with a 16-10 victory over the New Orleans Saints. In their preseason finale against the Raiders, the 49ers finished with a 24-24 tie, concluding the preseason with a 1-1-1 record. In Week 1 of the regular season against the New York Jets, the 49ers had a solid all-around performance, scoring in every quarter en route to a 32-19 win. Quarterback Brock Purdy completed 19-of-29 passes for 231 yards, while Jordan Mason impressed on the ground with 28 carries for 147 yards and a touchdown.

Vikings Preview 

On the Minnesota side, the Vikings had an impressive preseason, going undefeated in their matchups. They started with a narrow 24-23 win over the Raiders, followed by a dominant 27-12 victory against the Browns. In their exhibition finale, the Vikings cruised to a 26-3 blowout against the Eagles. In their regular-season opener on Sunday against the Giants, the Vikings looked sharp, leading 14-3 by halftime and ultimately securing a comfortable 28-6 victory. Sam Darnold threw for 208 yards with two touchdowns and an interception, while Aaron Jones led the rushing attack with 94 yards and a touchdown on 14 carries.

How I Use Rithmm Models for my Vikings vs 49ers AI Prediction

With Rithmm’s AI Picks model you are able to dive deep into just about any trend you can think of, below is just a snap shot of what I pulled for todays game. 

Against the Spread (ATS) Performance: 

• The 49ers have been strong ATS, going 13-4 in their last 17 games. However, they have struggled on the road recently, with a 1-4 ATS record in their last five away games. The Vikings, on the other hand, have been weaker ATS, posting a 3-8-1 record in their last 12 games, and they are winless in their last six home games ATS​

Recent Head-to-Head Matchups: 

• Minnesota has had the upper hand in recent meetings, winning their last two games against San Francisco, including a 22-17 victory in 2023. However, San Francisco did win a previous matchup in 2021​

Total Points Trends: 

• The under has hit in five of Minnesota's last six games. Meanwhile, when Kirk Cousins starts, the over has historically been a profitable bet, with a 56.8% success rate over the last 20 years

Matchup/League Facts:

• The Vikings ranked 1st in the NFL in forced fumbles (22) last season.
• The Vikings ranked T30th in the NFL in H2 win percentage (23.5) last season.
• The 49ers ranked T1st in the NFL in interceptions (22) last season.
• The 49ers ranked 1st in the NFL in red zone percentage (67.2%) last season.

My 49ers vs Vikings AI Prediction

I'll lean toward the 49ers in this matchup. San Francisco looked impressive in their recent win over the Jets, racking up 401 total yards, 25 first downs, and controlling the game with zero turnovers and 38:40 in time of possession. Their defense also did its part, holding New York to just 266 total yards (68 rushing), 14 first downs, and forcing two turnovers. 

On the other hand, Minnesota is coming off a solid win over the Giants, but their offensive stats were less inspiring. The Vikings managed 312 total yards (201 passing) and 17 first downs but struggled on third down, going just 3-of-10, and turned the ball over twice. While Minnesota has the potential to be competitive, especially if they find more consistency, I prefer San Francisco to cover the spread in this one.

Selection: 49ers -5.5

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