The Detroit Tigers take on the St. Louis Cardinals tonight at Busch Stadium in a cross-league matchup. Let’s take a look at my Tigers vs Cardinals prediction for May 20, including the latest Tigers vs Cardinals odds, picks, and best bets from my AI model.
Tonight’s Tigers vs Cardinals game kicks off at 7:45 PM ET from Busch Stadium. Detroit is looking to bounce back after a rough stretch, while the Cardinals are hoping to stay hot at home. Both teams are navigating injury challenges, which could influence the Tigers vs Cardinals pick.
The model gives a slight edge to the Tigers, projecting a 5.0–4.0 win. But with the Cardinals as +1.5 underdogs at home, there's some betting value to explore.
Injuries are playing a major role in this Tigers vs Cardinals prediction. Here's a look at who’s out:
Cardinals:
Tigers:
These absences, especially in Detroit's bullpen and outfield, add depth to the Tigers vs Cardinals injury outlook.
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Despite the model favoring Detroit by a narrow 5–4 margin, sportsbooks have the Cardinals listed as +1.5 underdogs. This shows there's no overwhelming favorite, which makes this Tigers vs Cardinals pick more nuanced.
When evaluating Tigers vs Cardinals trends, recent ATS performance tells the story:
These Tigers vs Cardinals trends support leaning toward St. Louis with the points.
Historically, the Cardinals have a slight edge in interleague matchups against the Tigers, though it’s a small sample size. The Tigers vs Cardinals prediction today is more heavily influenced by recent team form and roster health than historical data.
This pick comes from my Pre-Built MLB Rithmm Model, which incorporates:
According to my Rithmm model, the Cardinals have a 57.4% probability of covering the +1.5 run line, even if they don’t win outright. This makes them an appealing value for tonight’s Tigers vs Cardinals prediction.
Here’s the best Tigers vs Cardinals line for the Cardinals +1.5:
Based on model insights and current injuries, my Tigers vs Cardinals pick is Cardinals +1.5 (-111). The Tigers are depleted and haven’t covered well as favorites. St. Louis, meanwhile, has covered 2 of their last 3 as underdogs.
This Tigers vs Cardinals best bet offers both value and alignment with my AI-driven prediction.
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